Table 2. Measures of the various SBP parameters.
| Parameter | Image | Reference value | Median (IQR) | P-value |
|---|---|---|---|---|
| CNFL nerve fiber length (mm/mm2) | IVCM | 19.9 | 21.4 (3.3) | 0.020 |
| 19.9 | ||||
| 24.0 | ||||
| 23.0 | ||||
| Histology | 47.5 | 50.2 (6.0) | ||
| 53.9 | ||||
| 45.8 | ||||
| 52.9 | ||||
| CNFD nerve fiber density (n per mm2) | IVCM | 254.7 | 277.3 (70.5) | 0.021 |
| 187.5 | ||||
| 299.8 | ||||
| 334.2 | ||||
| Histology | 1442.0 | 1358.8 (270.1) | ||
| 1275.6 | ||||
| 1091.0 | ||||
| 1672.1 | ||||
| CNBD number of branching points (n per mm2) | IVCM | 146.4 | 163.5 (50.1) | 0.021 |
| 95.6 | ||||
| 180.6 | ||||
| 193.3 | ||||
| Histology | 914.3 | 847.6 (196.5) | ||
| 780.9 | ||||
| 678.7 | ||||
| 1064.5 | ||||
| CNFTo average weighted tortuosity (μm−1) | IVCM | 0.0788 | 0.081 (0.001) | 0.021 |
| 0.0830 | ||||
| 0.0813 | ||||
| 0.0820 | ||||
| Histology | 0.1006 | 0.095 (0.009) | ||
| 0.0860 | ||||
| 0.0910 | ||||
| 0.0990 | ||||
| CNCP Number of connecting points (n per mm2) | IVCM | 20.6 | 21.6 (3.5) | 0.021 |
| 22.2 | ||||
| 21.0 | ||||
| 31.3 | ||||
| Histology | 49.9 | 49.4 (2.6) | ||
| 54.9 | ||||
| 48.9 | ||||
| 47.2 | ||||
| CNSFL average single-fiber length (μm) | IVCM | 73.1 | 74.1 (10.9) | 0.021 |
| 101.8 | ||||
| 75.1 | ||||
| 63.8 | ||||
| Histology | 27.6 | 32.18 (9.55) | ||
| 37.0 | ||||
| 36.7 | ||||
| 26.3 | ||||
| CNFTh average weighted nerve fiber thickness (μm) | IVCM | 2.244 | 2.224 (0.057) | 0.309 |
| 2.203 | ||||
| 2.198 | ||||
| 2.302 | ||||
| Histology | 2.225 | 2.202 (0.024) | ||
| 2.157 | ||||
| 2.207 | ||||
| 2.198 |