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. 2017 Feb 28;2017:6726901. doi: 10.1155/2017/6726901

Figure 5.

Figure 5

Constitutive activation of FoxO1 results in decrease of β cell markers. (a) qRT-PCR analysis of FoxO1 mRNA levels in human pancreatic progenitor cells transfected with retrovirus expressing either vector or constitutively active FoxO1 (FoxO1-AAA). Data were normalized against the level of GAPDH and expressed as fold change relative to vector (low panel). Values are means ± SEM of 4 independent experiments per each group. ∗∗p < 0.01. (b) qRT-PCR analysis of β cell markers in human pancreatic progenitor cells transfected with retrovirus expressing either vector or constitutively active FoxO1 (FoxO1-AAA). Data were expressed as fold change relative to vector and are means ± SEM of 3 to 5 independent experiments per each group. ∗ or ∗∗, p < 0.05 or 0.01.