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. 2017 Feb 28;2017:8316560. doi: 10.1155/2017/8316560

Figure 5.

Figure 5

NLRP3 deletion ameliorates UUO-induced cell apoptosis in UUO mice. Representative images of TUNEL staining are shown ((a), magnification, ×200). Bar graph indicates the mean number of TUNEL-positive tubular cells per field (b). Expression of caspase 3 protein was detected in kidney samples (c). Semiquantitative analysis of cleaved caspase 3 normalized against β-actin (d). Data represent the mean ± SEM (n = 6). ∗P < 0.05, compared with WT/Sham group, #P < 0.05, NLRP3−/−/U14 group versus WT/U14 group. U1, U3, U7, and U14 indicate that mice were sacrificed on days 1, 3, 7, and 14 after UUO.