Table 3.
Control diet | Western diet | Reversion | |||||||
---|---|---|---|---|---|---|---|---|---|
CON | MI | MI + SEVO | CON | MI | MI + SEVO | CON | MI | MI + SEVO | |
Baseline | |||||||||
SBP [mmHg] | 137 ± 32 | 157 ± 31 | 152 ± 44 | 134 ± 47 | 143 ± 22 | 150 ± 22 | 152 ± 31 | 152 ± 40 | 171 ± 28 |
DBP [mmHg] | 108 ± 36 | 132 ± 22 | 110 ± 39 | 93 ± 39 | 112 ± 21 | 111 ± 23 | 112 ± 25 | 115 ± 36 | 128 ± 18 |
MAP [mmHg] | 116 ± 29 | 138 ± 20 | 124 ± 40 | 107 ± 42 | 122 ± 21 | 124 ± 22 | 125 ± 27 | 128 ± 37 | 143 ± 21 |
HR [bpm] | 367 ± 64 | 405 ± 36 | 414 ± 32 | 367 ± 67 | 403 ± 18 | 381 ± 29 | 395 ± 49 | 390 ± 43 | 397 ± 39 |
Ischemia | |||||||||
SBP [mmHg] | 108 ± 26 | 104 ± 20 | 83 ± 28 | 122 ± 12 | 107 ± 10 | 102 ± 11 | 118 ± 22 | 100 ± 25 | 100 ± 25 |
DBP [mmHg] | 74 ± 23 | 74 ± 13 | 55 ± 11 | 65 ± 4 | 68 ± 14 | 60 ± 10 | 69 ± 13 | 60 ± 12 | 56 ± 15 |
MAP [mmHg] | 83 ± 14 | 82 ± 4 | 64 ± 17 | 84 ± 6 | 81 ± 11 | 74 ± 8 | 85 ± 14 | 73 ± 14 | 70 ± 16 |
HR [bpm] | 276 ± 54 | 287 ± 22 | 283 ± 25 | 294 ± 22 | 301 ± 39 | 297 ± 27 | 271 ± 26 | 294 ± 39 | 283 ± 33 |
Reperfusion | |||||||||
SBP [mmHg] | 114 ± 31 | 91 ± 24 | 69 ± 24 | 110 ± 24 | 91 ± 33 | 93 ± 18 | 125 ± 30 | 92 ± 27 | 97 ± 13 |
DBP [mmHg] | 82 ± 32 | 63 ± 18 | 55 ± 9 | 72 ± 17 | 60 ± 30 | 56 ± 12 | 82 ± 26 | 54 ± 17∗ | 58 ± 16 |
MAP [mmHg] | 91 ± 28 | 71 ± 15 | 59 ± 14 | 85 ± 18 | 71 ± 30 | 68 ± 12 | 96 ± 26 | 66 ± 19∗ | 71 ± 13 |
HR [bpm] | 286 ± 46 | 268 ± 16 | 289 ± 20 | 292 ± 24 | 303 ± 60 | 309 ± 20 | 302 ± 34 | 277 ± 29 | 288 ± 32 |
Data are mean ± SD, n = 7–10, two-way ANOVA with Bonferroni post hoc analyses, and ∗p < 0.05 MI versus CON.
SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial blood pressure; HR: heart rate.