Figure 6. Deletion of the β₂AR gene normalizes the cardiac functional reserve response to adrenergic stimulation after HFD feeding.

After HFD feeding, cardiac haemodynamics were measured in wild‐type (WT) and β₂AR‐KO mice before and after i.p. injection of ISO (0.2 mg kg⁻¹). The maximal dP/dt (A), minimal −dP/dt (B), cardiac output (C) and heart rate (D) were recorded and plotted in bar graphs (n = 6). ^* P < 0.05 and ^** P < 0.01, by Student's unpaired t test between groups.