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. 2017 Mar 15;595(6):2147–2160. doi: 10.1113/JP273581

Figure 4. Spontaneous excitability is increased at the COX10‐depleted DG–CA3 synapse.

Figure 4

A, representative spontaneous EPSC (sEPSC) recordings from CA3 PCs from control (left) and COX10‐deficient mice (right). B and C, neither sEPSC average amplitude (B) nor frequency (C) was substantially increased in COX10‐deficient (n = 8 mice, blue) or control mice (n = 7 mice, red). D, the cumulative distribution of sEPSC amplitude, however, displayed a clear tendency towards larger EPSCs in the COX10‐deficient mice. Statistics shown: ns, P > 0.05; *** P < 0.001.