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. 2017 Feb 7;595(6):1987–2000. doi: 10.1113/JP272995

Figure 7. Schematic model illustrates formation of N‐cadherin AJs between VSMCs in the vessel wall of SCAs.

Figure 7

Upper: cross‐sectional view of vessel wall. Lower: transection view of the vessel wall. Increase of transmural pressure induces the SCA myogenic response and vasoconstriction. This process leads to enhanced cell–cell contacts, resulting in increase of the cell–cell adhesions and mechanical coupling. PE enhanced the formation of N‐cadherin AJs between VSMCs, whereas ACh induced the disassembly of AJs. PL, low pressure; PH, high pressure. [Color figure can be viewed at wileyonlinelibrary.com]