Table 2.

Fixed parameters in the pancreatic duct model

	Parameter	Value	Unit
Apical membrane
SLC26A6	n	2 / 1*
	K Cl	5	mm
	K HCO3	12 / 6*	mm
CFTR	P HCO3 /P Cl	0.4
H+,K+‐ATPase	K H	5 × 10−4	mm
	K K	3	mm
H+ permeability	P H	10−3	cm s−1
CO2 permeability	P CO2	0.7	cm s−1
NH3 permeability	P NH3	0.1	cm s−1
Water permeability	L p	3 × 10−5	cm s−1 atm−1
Basolateral membrane
NBC1	K Na	500	mm
	K HCO3	30	mm
	R l / k	100
	K als	10.2	mm
	n Cl	−1
NHE1	G NHE	0.485	nmol s−1 cm−2
	K Na	100	mm
	K H	5 × 10−4	mm
	K als	1.4 × 10−4	mm
	n H	2.5
AE2	K Cl	10	mm
	K HCO3	1	mm
NKCC1	K Na	63.3	mm
	K K	108	mm
	K Cl	4.6	mm
Na+,K+‐ATPase	E rev	−200	mV
	K K	1.4	mm
	K Na	25	mm
H+,K+‐ATPase	K H	5 × 10−4	mm
	K K	3	mm
H+ permeability	P H	10−3	cm s−1
CO2 permeability	P CO2	1	cm s−1
NH3 permeability	P NH3	0.1	cm s−1
Water permeability	L p	3 × 10−5	cm s−1 atm−1
Tight junction
K+ permeability	P K	6 × 10−3	cm s−1
Na+ permeability	P Na	6 × 10−3	cm s−1
Basement membrane
H+ permeability	P H	1	cm s−1
CO2 permeability	P CO2	103	cm s−1
NH3 permeability	P NH3	103	cm s−1
Other solute permeabilities	P S	10−3	cm s−1
Water premeability	L p	102	cm s−1 atm−1

^*Alternative values are shown for the 1:2 and 1:1 Cl^–/HCO₃ ^– stoichiometries of SLC26A6.