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. 2017 Feb 8;595(6):1947–1972. doi: 10.1113/JP273306

Table 6.

Steady‐state values of variables in the perfused duct model in resting and stimulated conditions for the alternative 1:2 and 1:1 stoichiometries of SLC26A6

Resting Stimulated
[HCO3 ]l Experimental data 1:2 1:1 Experimental data 1:2 1:1
[K+]c (mm) 126.4 126.4 116.6 116.9
[Na+]c (mm) 11.7 ± 1.2a 9.9 10.0 17.2 ± 1.0a 19.4 19.3
[Cl]c (mm) low 31.2 ± 2.6b 28.6 28.7 35.5 ± 3.4b 33.6 34.2
high 12.5 ± 3.2b 14.5 12.0 6.7 ± 0.7b 3.2 3.5
[HCO3 ]c (mm) low 20.7 20.7 19.2 19.3
20.7* 19.8*
high 23.6 23.7 21.4 21.3
[X]c (mm) 120.0 119.7 115.5 114.8
Osm c (mOsm) 305.6 305.6 304.4 304.6
pHc low 7.34 7.34 7.31 7.31
7.34 ± 0.01a 7.32 ± 0.01a
high 7.39 7.40 7.35 7.35
E bl (mV) low −59.5 ± 3.6c −65.5 −66.7 −52.5 ± 2.3c −52.0 −53.3
high −64.3 ± 2.7c −71.9 −72.1 −61.8 ± 2.4c −70.5 −69.5
E tj (mV) −2.1 −1.9 −8.8 −7.7
V c (μl cm−2) 1.08 1.08 1.11 1.11

a(Ishiguro et al. 1996); b(Ishiguro et al. 2002a); c(Ishiguro et al. 2002b).

*Estimated from pHc.