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. 2017 Mar 6;216(3):779–792. doi: 10.1083/jcb.201512012

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© 2017 Genentech

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 3. — IRF4 directly regulates DC immunosuppressive programming. ChIPseq analysis for histone H3K27 acetylation and H3K4 trimethylation was performed on MHCII^hi (black) and MHCII^lo (gray) populations purified from unstimulated BMDCs. MHCII^lo track is inverted and juxtaposed with MHCII^hi track to facilitate comparison of signals. Our previously reported ChIPseq analysis for IRF4 binding in total CD11c⁺ BMDCs is displayed in red. Data are representative of two independent experiments.