Table 2.
Association of clinical and ultrasonographic (US) features with histology of 69 nodules with indeterminate cytological diagnosis. CFD, color-flow Doppler.
| Clinical and US features | Benign (n = 52) |
Malignant (n = 17) |
p |
|---|---|---|---|
| Gender | |||
| Male | 14 (26.29%) | 4 (23.52%) | 0.527 |
| Female | 38 (73.1%) | 13 (76.47%) | |
|
| |||
| Age (yr) | |||
| Median age | 58 (13–77) | 50 (20–75) | 0.347 |
|
| |||
| Morphology | |||
| Taller than wide | 7 (13.46%) | 6 (35.3%) | 0.046 |
| Round/oval shape | 45 (86.53%) | 11 (64.70%) | |
|
| |||
| Median nodule volume (ml) |
1.2 (0.12–12) | 0.44 (0.1–8.6) | 0.016 |
|
| |||
| Margin | |||
| Irregular | 15 (28.8%) | 11 (64.70%) | 0.008 |
| Regular | 37 (71.1%) | 6 (35.3%) | |
|
| |||
| Microcalcification | |||
| Yes | 9 (17.30%) | 7 (41.2%) | 0.043 |
| No | 43 (82.7%) | 10 (58.9%) | |
|
| |||
| Echogenicity | |||
| Hypoechogen | 25 (48.1%) | 13 (76.47%) | 0.021 |
| Isoechogen | 19 (36.5%) | 1 (5.88%) | |
|
| |||
| Echostructure | |||
| Mixed | 8 (15.4%) | 3 (17.64%) | 0.545 |
| Solid | 44 (84.6%) | 14 (82.35%) | |
|
| |||
| Color-flow Doppler | |||
| CFD 1 | 11 (21.15%) | 5 (29.41%) | 0.755 |
| CFD 2 | 6 (11.5%) | 1 (5.88%) | |
| CFD 3 | 35 (67.30%) | 11 (64.70%) | |
|
| |||
| Nodularity | |||
| Uninodular | 20 (38.5%) | 5 (29.41%) | 0.356 |
| Multinodular | 32 (61.53%) | 12 (70.6%) | |