Table 1. Screening of the Lewis Acid Catalysts for Ugi-Tetrazole Adduct.
entry | catalyst | conc. (equiv) | yield (%)a |
---|---|---|---|
1 | - | - | 45 |
2 | ZnCl2 | 0.1 | 72 |
3 | SnCl2 | 0.1 | 60 |
4 | (CF3SO3)2Zn | 0.1 | 62 |
5 | CF3SO3Ag | 0.1 | 43 |
6 | CF3SO3K | 0.1 | 47 |
7 | (CF3SO3)2Mg | 0.1 | 75 |
8 | CF3SO3Li | 0.1 | 53 |
9 | (CF3SO3)3In | 0.1 | 38 |
10 | (CF3SO3)3Al | 0.1 | 47 |
Isolated yield.