Figure 4.
Coadministration of iNKT cell ligands together with protein provides therapeutic anti-tumor activity. (A) Growth of s.c. implanted E.G7-OVA tumors was assessed in animals treated therapeutically 4 days after tumor challenge (as indicated by downward-pointing arrows) by i.v. injection of OVA protein alone, α-GalCer or OCH alone, or a combination of OVA together with either iNKT cell ligand. (B) Induction of OVA257–264–specific CD8+ T cell responses was measured in the blood 7 days after therapy described in A was initiated.