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. 2010 Aug 18;3(4):158–169. doi: 10.1111/j.1752-8062.2010.00212.x

Figure 1.

Figure 1

Fullerene derivatives inhibit anti‐FcɛRI‐dependent increases in intracellular calcium and ROS levels. Cells were incubated with or without FD (10 μg/mL) overnight. The next day cells were challenged with anti‐FcɛRI (3B4; 1 μg/mL) and calcium stores release was determined by the 340/380 nm ratio (A and B) and ROS measured by DCF detection at 523 nm (C and D). A and C contain cells incubated with the TGA FD and B and D contain cells incubated with the Inos FD (10 μg/mL). The dark gray squares are the unchallenged negative control, dark thick solid black line is the anti‐FcɛRI challenged positive control cells, and the two light gray lines (hashed and double line) are the anti‐FcɛRI challenged cells pretreated with respective FD. Results are representative of at least three separate experiments.