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Comparison of tumor cell lines and primary tumor cells as fusion partners. Groups of 10 mice were immunized with 5.0 × 105 electrofused cells on days 0 and 14. A lethal subcutaneous tumor challenge with M3 tumor cells was performed on day 21. Tumor size was measured twice a week. Immunization with either of the electrofusion vaccines resulted in a statistically significant increase in survival compared to vehicle‐treated mice (p < 0.0001).
