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. 2014 Nov 10;8(2):100–106. doi: 10.1111/cts.12234

Figure 4.

Figure 4

Association between lncRNAs and left ventricular hypertrophy. Data shown are from a public microarray dataset (GSE48110). Mice were subjected to TAC or sham operation and were treated with BET bromodomian inhibitor JQ1 or vehicle (DMSO) for 3, 11, or 28 days. Hearts were harvested and gene expression was analyzed by Affymetrix Mouse Gene 1.0 ST microarray. Graph bars represent the expression values of the four lncRNAs 2900055J20Rik, Gm14005, Gm10400, and Dancr extracted from microarray data and expressed as log2. *p < 0.05 vs. sham, **p < 0.01 vs. sham, #p < 0.05 vs. TAC, ##p < 0.01 vs. TAC (n = 3 per group). Veh = vehicle (DMSO).