Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 5;10(1):42–49. doi: 10.1111/cts.12431

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors. Clinical and Translational Science published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

(a) Individual 4β‐hydroxycholesterol (4βOHC) concentrations in patients with rheumatoid arthritis (RA; n = 41) before vs. after disease‐modifying antirheumatic drugs (bDMARDs) treatment and in noninflammatory reference subjects (right panel; n = 52), (b) relative changes in 4βOHC (paired after:before ratios) in patient subgroups treated with tumor necrosis factor alpha (TNFα) inhibitors (n = 31), interleukin (IL)‐6 inhibitors (n = 5) and B‐cell inhibitors (n = 5), and (c) simple plot of relative changes in 4βOHC according to individual baseline values in the whole RA population (dotted linear trend line added for visual purpose).