Table 1.

Table summarizing the connectivity map data for DMPK suppressors

	Drug	Drug Class	DMPK mRNA level
			Connectivity
			Map Data
			10 μM: 6 hours
			(fold expression)
1	Tomelukast	Leukotriene antagonist	0.56
2	Sulindac sulfide	XSAID	0∼64
3	8‐Azaguanine	Purine analog	0.71
4	Santonin	Anthelminthic	0.72
5	Prilocaine	Na channel blocker	0.75
6	Procainamide	Na channel blocker	0.75
7	Splitomicin	Sirtuin inhibitor	0.76
8	Apigenin	Flavone (yellow)	0.80
9	Liothyronine	Thyroid hormone	0.80
10	Mexiletine	Na Channel Blocker	0.80
11	Sparteine	Na Channel Blocker	0.80

Connectivity map data indicates the original fold expression values provided by the Broad Institute used initial ranking of the compounds. Sodium channel inhibitors are indicated by bold type.