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. 2017 Mar 15;14:47. doi: 10.1186/s12974-017-0819-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Lipopolysaccharide-stimulated MP activate primary cortical microglia. Enriched MP were isolated from control and LPS-stimulated BV2 microglia and were co-cultured with primary cortical microglia for 24 h. Pro-inflammatory mediators (IL-1β, TNF-α, miR-155, IL-6, CCL2, and NOS2) were significantly increased in primary microglia treated with LPS MP (*p < 0.05, **p < 0.001, and ***p < 0.001 vs naïve; ^p < 0.05 and ^^p < 0.01 vs control MP; one-way ANOVA with Student-Newman-Keuls correction for multiple comparisons; n = 5/group). Bars represent mean ± S.E.M.