Table 2.

Meta-analysis comparing OR of favorable outcome, stratified by result analysis, primary outcome, and funding source

Funding source	Per-protocol, OR (95% CI)	Intention-to-treat, OR (95% CI)	Clinical outcome, OR (95% CI)	Surrogate outcome, OR (95% CI)
For-profit	1.92 (1.72–2.14)	1.74 (1.58–1.92)	1.50 (1.40–1.61)	3.72 (2.53–5.51)
Mixed	1.34 (1.25–1.43)a	1.30 (1.22–1.38)a	1.27 (1.16–1.34)a	1.57 (1.26–1.95)a
Nonprofit	1.32 (1.26–1.39)a	1.33 (1.26–1.40)a	1.27 (1.19,1.37)a	1.62 (1.46–1.76)a

^aStatistical difference compared with for-profit-funded research (p < 0.05)