Figure 1.

(A) H&E and (B) Masson's trichrome staining of the control group rat lung tissue samples shows a normal appearance (grade 0). (C) H&E and (D) Masson's trichrome staining of bleomycin-induced PF group rat lung tissue samples with significant alveolitis and fibrosis. (E) H&E and (F) Masson's trichrome staining of lung tissue samples from bleomycin-induced PF rats treated with bosentan show reduced alveolitis and fibrosis compared with the bleomycin-induced PF group rats. Magnification, ×100. H&E, hematoxylin and eosin; PF, pulmonary fibrosis.