Table 2.
Cisplatin | Paclitaxel | |||
---|---|---|---|---|
Fold change* (p‐value+) | Fold change* (p‐value+) | |||
Treated cells‡ | Untreated cells§ | Treated cells‡ | Untreated cells§ | |
miR‐143 | 2.4 (0.031) | 1.4 (n.s.) | −1.4 (n.s.) | −2.2 (0.019) |
miR‐145 | 3.5(0.028) | 7.6 (0.009) | 1.0 (n.s.) | 2.0 (0.044) |
miR‐183 | 3.5 (0.013) | 10.5 (0.001) | −3.5 (0.013) | 1.4 (n.s.) |
miR‐96 | −1.5 (n.s.) | 2.5 (0.021) | −1.9 (0.048) | 1.3 (n.s.) |
miR‐182 | −1.9(0.039) | 2.6 (0.008) | −2.0 (0.034) | 1.0 (n.s.) |
Positive and negative values reflect increase and decrease in miRNA expression, respectively.
n.s. stands for not significant variations (p‐value > 0.05).
Fold changes in comparison with the relative levels of miRNAs detected in the 48‐hour treated cells.
Compared with the average of the relative miRNA levels measured in untreated (control) cells.