Table 1.
Indices of diastolic dysfunction and LV remodeling
| Index | Normal values | Diastolic dysfunction and LV remodeling | Women with index at baseline, n (%) | Men with index at baseline, n (%) |
|---|---|---|---|---|
| E/A ratio | 1.0–2.0 | < 1.0; > 2.0 | < 1.0: n = 629 (54.0%); > 2.0: n = 12 (1.0%) | < 1.0: n = 505 (58.8%); > 2.0: n = 14 (1.6%) |
| EDT | 140–220 ms | < 140 ms; > 220 ms | < 140 ms: n = 120 (10.3%); > 220 ms; n = 163 (14.0%) | < 140 ms: n = 73 (8.1%); > 220 ms; n = 188 (21.0%) |
| IVRT | 60–110 ms | < 60 ms; > 110 ms | < 60 ms: n = 25 (2.1%); > 110 ms: n = 23 (2.0%) | < 60 ms: n = 12 (1.3%); > 110 ms: n = 29 (3.2%) |
| Average e’ wave | ≥ 9 cm/s | < 9 cm/s | n = 184 (15.8%) | n = 125 (14.0%) |
| E/e’ ratio | < 8 | ≥ 8 | n = 247 (21.2%) | n = 149 (16.6%) |
| LA size | < 2.2 cm/m2 | Moderately enlarged: 2.2–2.79 cm/m2; severely enlarged: ≥ 2.8 cm/m2 | Moderately enlarged: n = 319 (27.4%); severely enlarged: n = 26 (2.2%) | Moderately enlarged: n = 176 (19.6%); severely enlarged: n = 14 (1.6%) |
| LV remodeling | LV mass ≤ 95 g/m2 in women or ≤ 115 g/m2 in men, and RWT ≤ 0.42 | Concentric remodeling: LV mass ≤ 95 g/m2 in women or ≤ 115 g/m2 in men, and RWT > 0.42; concentric hypertrophy: LV mass > 95 g/m2 in women or > 115 g/m2 in men, and RWT > 0.42; eccentric hypertrophy: LV mass > 95 g/m2 in women or > 115 g/m2 in men, and RWT ≤ 0.42 | Concentric remodeling: n = 45 (3.9%); concentric hypertrophy: n = 40 (3.4%); eccentric hypertrophy: n = 206 (17.7%) | Concentric remodeling: n = 39 (4.4%); concentric hypertrophy: n = 35 (3.9%); eccentric hypertrophy: n = 147 (16.4%) |
Abbreviations: EDT E-wave deceleration time, IVRT Isovolumetric relaxation time, LA Left atrium, LV Left ventricle, RWT Relative wall thickness