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. 2017 Mar 7;8:9. doi: 10.1186/s13229-017-0125-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Social approach behavior in juvenile offspring who were exposed to prenatal immune challenge (POL) or prenatal vitamin D treatment (Vit_D). a Compared with control mice poly(I:C)-treated offspring spent less time with a novel conspecific compared to an inanimate object (approaching chance level 50%) demonstrating impaired social approach behavior (*P < 0.05). This impairment was not evident when Vit_D was co-administered (#P = 0.06) suggesting Vit_D blocked the negative effects of MIA on social functions. b Prenatal exposures had no effects on locomotion in this test. All values are mean ± SEM (n = 8)