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. 2017 Mar 15;10:15. doi: 10.1186/s12920-017-0255-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The copy number inference results of different methods on a simulated sample. Major and total copy numbers inferred by CLImAT-HET, OncoSNP-SEQ and CLImAT are compared with the ground truth, respectively. The predefined major and total copy numbers of all segments in simulation study are treated as underlying truth. The results show that CLImAT-HET infers the correct copy numbers for 86% of all segments