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Expression of Survivin in myeloma cells treated with ASA and/or BTZ. (A) The MM1.S and RMPI-8226 cells were incubated with ASA, BTZ and ASA+BTZ for 48 h, respectively. The protein expression of Survivin was determined using western blot analysis. Each blot is representative of three independent experiments. (B) Integrated optical density data are presented as the mean ± standard deviation. *P<0.05. ASA, aspirin; BTZ, bortezomib.
