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. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: Paediatr Perinat Epidemiol. 2016 May 23;30(5):496–510. doi: 10.1111/ppe.12299

Frequency of preterm (<32 weeks’ gestational age) and very preterm (<32 weeks’ gestational age) birth among all livebirths surviving beyond 1 year and among cerebral palsy (CP) cases at age 8 years, by surveillance year, by race and ethnicity, sex, co-occurring epilepsy, and co-occurring autism spectrum disorder (ASD).

Surveillance year 2006 (birth year 1998) Surveillance year 2008 (birth year 2000) Surveillance year 2010 (birth year 2002) Test for trend P-value
Total number of births surviving to age 1 year 125 166 130 884 128 722
Number with gestational age information at birth 125 025 130 803 128 676
 % Preterm (95% CI) 11.9 (11.7, 12.0) 11.9 (11.7, 12.0) 12.5 (12.3, 12.6) <0.001
 % Very preterm (95% CI) 1.8 (1.7, 1.9) 1.8 (1.8, 1.9) 1.8 (1.2, 1.4) 0.381
Total number of white, non-Hispanic births surviving to age 1 year (% of total white non-Hispanic births) 75 141 74 437 70 688
 % Preterm (95% CI) 9.9 (9.7, 10.1) 10.3 (10.0, 10.5) 10.8 (10.6, 11.1) <0.001
 % Very preterm (95% CI) 1.2 (1.1, 1.3) 1.3 (1.2, 1.3) 1.3 (1.2, 1.4) 0.161
Total number of black, non-Hispanic births surviving to age 1 year (% of total black non-Hispanic births) 37 587 38 898 37 005
 % Preterm (95% CI) 16.6 (16.2, 16.9) 16.1 (15.7, 16.5) 17.1 (16.7, 17.5) 0.057
 % Very preterm (95% CI) 3.3 (3.1, 3.5) 3.2 (3.1, 3.4) 3.1 (2.9, 3.2) 0.075
Total number of Hispanic births surviving to age 1 year (% of total Hispanic births) 6156 9348 11 831
 % Preterm (95% CI) 8.5 (7.8, 9.2) 9.1 (8.5, 9.7) 9.4 (8.9, 10.0) 0.038
 % Very preterm (95% CI) 1.0 (0.8, 1.3) 0.9 (0.7, 1.1) 1.1 (0.9, 1.3) 0.367
CP cases with no documented postneonatal aetiology (age 8 years) with available birth certificate data
 Total number of CP cases 291 294 267
 Number with gestational age information at birth 290 294 267
  % Preterm (95% CI) 52.1 (46.2, 57.9) 52.0 (46.2, 57.9) 48.7 (42.6, 54.9) 0.213
  % Very preterm (95% CI) 35.9 (30.3, 41.7) 35.4(30.0, 41.2) 31.1 (25.7, 37.1) 0.241
 Number of white non-Hispanic cases 161 147 118
  % Preterm (95% CI) 44.7 (37.0, 52.7) 45.6 (37.4, 54.0) 43.2 (34.2, 52.7) 0.825
  % Very preterm (95% CI) 22.2 (17.9, 31.7) 27.9 (21.0, 36.0) 23.7 (16.6, 32.6) 0.989
 Number of black non-Hispanic cases 103 111 110
  % Preterm (95% CI) 61.2 (51.0, 70.5) 58.6 (48.8, 67.7) 55.5 (45.7, 64.8) 0.398
  % Very preterm (95% CI) 54.2 (42.4, 62.3) 44.1 (34.8, 53.9) 39.1 (30.1, 48.9) 0.052
 Number of Hispanic CP cases 13 25 25
  % Preterm (95% CI) 76.9 (46.0, 93.8) 52.0 (31.8, 71.7) 44.0 (25.0, 64.7) 0.068a
  % Very preterm (95% CI) 53.9 (26.1, 79.6) 28.0 (12.9, 49.6) 24.0 (10.2, 45.5)
 Number of boys 158 181 143
  % Preterm (95% CI) 50.6 (42.6, 58.6) 54.7 (47.2, 62.1) 49.0 (40.1, 57.4) 0.795
  % Very preterm (95% CI) 34.2 (27.0, 42.2) 35.4 (28.4, 42.9) 33.6 (26.0, 42.0) 0.919
 Number of girls 132 113 124
  % Preterm (95% CI) 53.8 (44.9, 62.4) 47.8 (38.4, 57.4) 48.4 (39.4, 57.5) 0.383
  % Very preterm (95% CI) 37.9 (29.7, 46.8) 35.4 (26.8, 45.0) 28.2 (20.7, 37.1) 0.105
 Number with co-occurring epilepsy 99 122 114
  % Preterm (95% CI) 43.4 (33.6, 53.8) 46.7 (37.7, 55.9) 46.5 (37.2, 56.0) 0.665
  % Very preterm (95% CI) 29.3 (20.8, 39.4) 24.6 (17.5, 33.4) 28.1 (20.3, 37.4) 0.869
 Number with no co-occurring epilepsy 191 172 153
  % Preterm (95% CI) 56.5 (49.2, 63.6) 55.8 (48.1, 63.3) 50.3 (42.8, 59.1) 0.263
  % Very preterm (95% CI) 39.3 (32.4, 46.6) 43.0 (35.6, 50.8) 33.3 (26.1, 41.5) 0.303
 Number with co-occurring ASD 20 20 23
  % Preterm (95% CI) 55.0 (32.1, 76.2) 50.0 (27.9, 72.2) 52.2 (31.2, 72.6) 0.862
  % Very preterm (95% CI) 30.0 (12.8, 54.3) 30.0 (12.8, 54.3) 34.8 (17.2, 57.2) 0.733
 Number with no co-occurring ASD 270 274 244
  % Preterm (95% CI) 51.9 (45.7, 57.9) 52.2 (46.1, 58.2) 48.4 (42.0, 54.8) 0.439
  % Very preterm (95% CI) 36.3 (30.6, 42.4) 35.8 (30.2, 41.8) 30.7 (25.1, 37.0) 0.192

ASD, autism spectrum disorder; CI, confidence interval; CP, cerebral palsy.

a

P-value not calculated due to small expected cell sizes.