Overall survival rates of gastric cancer patients according to the expression of (A) KLF4, (B) Oct4, (C) Nanog, (D) c-Myc and (E) SOX2. Kaplan-Meier analysis revealed a significantly less favorable overall survival rate in patients with low KLF4 expression compared with those with high expression (log-rank, P=0.0740; Wilcoxon, P=0.0359). MV, mean value of immunohistochemistry scores. KLF4, Krüppel-like factor 4; Oct4, octamer-binding transcription factor 4; c-Myc, avian myelocytomatosis viral oncogene homolog; SOX2, sex-determining region Y-box 2.