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. 2016 Dec 14;13(2):819–826. doi: 10.3892/ol.2016.5499

Table II.

Association between patient characteristics and KLF4 expression in gastric cancer of various stages.

All stages Stage II–III


KLF4 expression KLF4 expression


Variable Low (n=36) High (n=72) P-value Low (n=15) High (n=33) P-value
Age (years), median 69 70 0.76 70 69 0.76
Gender, n 0.75 0.36
  Male 25 57 10 26
  Female 11 15   5   7
Tumor invasion, n 0.27 0.27
  ≤T2 20 35 13 28
  >T2 16 37   2   5
LN metastasis, n 0.65 0.21
  Positive 27 51 14 26
  Negative   9 21   1   7
Number of metastatic LNs, n 0.87 0.38
  <7 26 53   9 24
  ≥7 10 19   6   9
M stage, n 0.76
  0 25 52
  1 11 20
Lymphovascular invasion, n 0.41 0.23
  Positive 22 38 15 30
  Negative 14 34   0   3
Vascular invasion, n 0.54 0.29
  Positive 25 54 13 24
  Negative 11 18   2   9
Histology, n 0.41 0.33
  Intestinal 22 38 10 17
  Diffuse 14 34   5 16
Tumor size (cm)
  Median 5.0 5.6 0.43a 6.0 5.0 0.35a
  <5, n 15 27   7 14
  ≥5, n 21 45 0.67b   8 19 0.78b
Preoperative chemotherapy, n 0.37 0.5
  Administered   8 11   4   6
  Not administered 28 61 11 27
Postoperative chemotherapy, n 0.33 0.28
  Administered 18 43 10 27
  Not administered 18 29   5   6
a

P-value for comparison of median tumor size

b

P-value for comparison of tumor size <5 vs. ≥5 cm. KLF4, Krüppel-like factor 4; LN, lymph node; M stage, metastasis stage.