Table II.
All stages | Stage II–III | |||||
---|---|---|---|---|---|---|
KLF4 expression | KLF4 expression | |||||
Variable | Low (n=36) | High (n=72) | P-value | Low (n=15) | High (n=33) | P-value |
Age (years), median | 69 | 70 | 0.76 | 70 | 69 | 0.76 |
Gender, n | 0.75 | 0.36 | ||||
Male | 25 | 57 | 10 | 26 | ||
Female | 11 | 15 | 5 | 7 | ||
Tumor invasion, n | 0.27 | 0.27 | ||||
≤T2 | 20 | 35 | 13 | 28 | ||
>T2 | 16 | 37 | 2 | 5 | ||
LN metastasis, n | 0.65 | 0.21 | ||||
Positive | 27 | 51 | 14 | 26 | ||
Negative | 9 | 21 | 1 | 7 | ||
Number of metastatic LNs, n | 0.87 | 0.38 | ||||
<7 | 26 | 53 | 9 | 24 | ||
≥7 | 10 | 19 | 6 | 9 | ||
M stage, n | 0.76 | – | ||||
0 | 25 | 52 | – | – | ||
1 | 11 | 20 | – | – | ||
Lymphovascular invasion, n | 0.41 | 0.23 | ||||
Positive | 22 | 38 | 15 | 30 | ||
Negative | 14 | 34 | 0 | 3 | ||
Vascular invasion, n | 0.54 | 0.29 | ||||
Positive | 25 | 54 | 13 | 24 | ||
Negative | 11 | 18 | 2 | 9 | ||
Histology, n | 0.41 | 0.33 | ||||
Intestinal | 22 | 38 | 10 | 17 | ||
Diffuse | 14 | 34 | 5 | 16 | ||
Tumor size (cm) | ||||||
Median | 5.0 | 5.6 | 0.43a | 6.0 | 5.0 | 0.35a |
<5, n | 15 | 27 | 7 | 14 | ||
≥5, n | 21 | 45 | 0.67b | 8 | 19 | 0.78b |
Preoperative chemotherapy, n | 0.37 | 0.5 | ||||
Administered | 8 | 11 | 4 | 6 | ||
Not administered | 28 | 61 | 11 | 27 | ||
Postoperative chemotherapy, n | 0.33 | 0.28 | ||||
Administered | 18 | 43 | 10 | 27 | ||
Not administered | 18 | 29 | 5 | 6 |
P-value for comparison of median tumor size
P-value for comparison of tumor size <5 vs. ≥5 cm. KLF4, Krüppel-like factor 4; LN, lymph node; M stage, metastasis stage.