Skip to main content
. 2016 Mar 30;9(2):89–104. doi: 10.1111/cts.12391

Table 1.

Classes of immunotherapy agents in oncology

Active Immunotherapies
Classes Examples
Cancer vaccines Sipuleucel‐T
Cytokines Interleukin‐2, interferon‐α
Immunomodulatory mAbs Nivolumab, ipilimumab, pembrolizumab
Passive immunotherapies
Classes Examples
Cell‐based therapies Adoptive T‐cell therapy (e.g., TIL, TCR, CAR‐T)
Oncolytic viruses T‐Vec
Bi‐ and multispecific antibodies Blinatumomab
Tumor‐targeting mAbs Rituximab

mAbs, monoclonal antibodies; TIL, tumor infiltrating lymphocytes; TCR, T‐cell receptor; CAR‐T, chimeric antigen receptor T‐cell therapy; T‐Vec, Talimogene laherparepvec.