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. 2016 Dec 29;6(2):188–194. doi: 10.3892/br.2016.834

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Hematoxylin and eosin staining of myocarium in the different groups (magnification, ×400). Normal area of the three groups exhibited normal size cardiomyocytes, no hemorrhaging or neutrophil granulocyte infiltration. (A) Sham-surgery group, and normal areas of the (B) control and (C) PGE₂ groups. The RA and NRA in the control group exhibited cardiomyocyte degeneration, hemorrhaging, edema, and significant interstitial neutrophil granulocyte infiltration compared with the normal area of the same group. (D) Reperfusion area and (E) NRA of the control group. No significant cardiomyocyte degeneration was identified in the RA and NRA in the PGE₂ group, however, slight edema between the myocardial fibers, and mild neutrophil granulocyte infiltration was observed compared with the RA and NRA of the control group. (F) Reperfusion area and (G) NRA of the PGE₂ group. The intravascular yellow staining is Thioflavin-S stain. PGE₂, prostaglandin E₂; RA, reperfusion area; NRA, no-reflow area.