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. 2016 Dec 29;6(2):188–194. doi: 10.3892/br.2016.834

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Immunohistochemical analysis of the content and distribution of VEGF proteins (magnification, ×200). Myocardial VEGF protein expression levels of the control group markedly increased in the RA and NRA compared with the normal area. PGE₂ markedly upregulated the expression level of VEGF in the RA and NRA further when compared with the control group. Normal area of the (A) control and (B) PGE₂ groups; reperfusion area of the (C) control and (D) PGE₂ groups; NRA of the (E) control and (F) PGE₂ groups. VEGF, vascular endothelial growth factor; RA, reperfusion area; NRA, no-reflow area; PGE₂, prostaglandin E₂.