Table III.
Immunohistochemical analysis of the content and distribution of eNOS and VEGF proteins (integrated optical density/area ratio).
| Protein | Group | Normal area | Reperfusion area | No-reflow area |
|---|---|---|---|---|
| eNOS | Sham-surgery | 0.13±0.05 | – | – |
| Control | 0.12±0.01 | 0.34±0.08a | 0.41±0.04a | |
| PGE2 | 0.13±0.01 | 0.48±0.05a,b | 0.62±0.04a,b | |
| VEGF | Sham-surgery | 0.13±0.03 | – | – |
| Control | 0.12±0.05 | 0.24±0.03a | 0.26±0.06a | |
| PGE2 | 0.13±0.02 | 0.46±0.03a,b | 0.66±0.05a,b |
a
P<0.05 vs. normal area
b
P<0.05 vs. control group. eNOS, endothelial nitric oxide synthase; VEGF, vascular endothelial growth factor; PGE2, prostaglandin E2.