Expression of (A) CD147 and (B) VEGF in human lung carcinoma A549 cells, HUVEC and HFF, as detected using quantitative polymerase chain reaction. (C) CD147 co-localized with VEGF in the plasma membrane of A549 cells as detected by immunofluorescence. *P<0.05; **P<0.01. CD, cluster of differentiation; VEGF, vascular endothelial growth factor; HUVEC, human umbilical vein endothelial cells; HIFF, human infant foreskin fibroblasts; DAPI, 4′,6-diamidino-2-phenylindole.