(A and B) Expression of VEGF in A549-CD147, A549-pEGFP, A549-siCD147 and A549-pSicoR cells as detected by (A) quantitative polymerase chain reaction and (B) western blot analysis. (C) Vascular formations of human umbilical vein endothelial cells in the supernatant of A549-CD147, A549-pEGFP, A549-siCD147 and A549-pSicoR. **P<0.01. CD, cluster of differentiation; VEGF, vascular endothelial growth factor.