Table 1.
Summary statistics for the DUCore and DUPeriphery. Data are presented as mean (standard deviation). The area under curve (AUC) and ratio of peak perfusion compared to baseline are presented for all, fingertip and extensor DUs. Comparisons are the ratio of means (95% CIs) for the AUCs and peak perfusion/baseline ratios (GTN:placebo). Ratios with values greater than 1 indicate an increased response from glyceryl trinitrate (GTN) compared to placebo (PBO).
| All digital ulcers |
Fingertip digital ulcers |
Extensor digital ulcers |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| GTN | PBO | Comparison | GTN | PBO | Comparison | GTN | PBO | Comparison | |
| DUCore | |||||||||
| AUC (arbitrary perfusion units) | 26,245.42 (19,829.5) | 23,973.97 (18,607.44) | 1.2 (1.0 to 1.6) | 18,453.6 (10,721.8) | 16,506.8 (12,498.3) | 1.3 (0.7 to 2.2) | 32,924.1 (24,038.9) | 29,574.3 (21,161.2) | 1.2 (1.0 to 1.6) |
| Peak perfusion/baseline perfusion (ratio) | 2.5 (1.4) | 1.9 (0.9) | 1.2 (1.0 to 1.5) | 2.7 (1.7) | 2.1 (0.8) | 1.2 (0.8 to 1.9) | 2.3 (1.2) | 1.8 (1.0) | 1.2 (1.0 to 1.6) |
| DUPeriphery | |||||||||
| AUC (arbitrary perfusion units) | 62,025.2 (41,910.7) | 52,185.4 (33,734.3) | 1.1 (0.8 to 1.6) | 51,939.1 (42,923.2) | 49,019.0 (32,584.1) | 0.9 (0.4 to 2.0) | 70,670.4 (42,293.6) | 54,560.3 (36,606.2) | 1.4 (1.1 to 1.7) |
| Peak perfusion/baseline perfusion (ratio) | 2.2 (1.5) | 2.1 (1.4) | 1.0 (0.9 to 1.2) | 2.4 (2.2) | 2.5 (2.1) | 0.9 (0.7 to 1.2) | 2.0 (0.7) | 1.8 (0.8) | 1.1 (1.0 to 1.4) |