Table 1.
The genotype and allele frequencies of SNP 276G/T [BsmI (rs1501299)] and 45T/G [Smal (rs2241766)] in the breast cancer and control groups
| Genotype | Breast Cancer Patients | Control Patients | χ2 | p | OR; 95% CI |
|---|---|---|---|---|---|
| BsmI (rs1501299) | 97 (100.0) | 101 (100.0) | 2.694 | 0.260 | |
| GG | 44 (45.4) | 56 (55.4) | 2.013 | 0.156 | 0.667 (0.381 – 1.168) |
| GT | 44 (45.4) | 40 (39.6) | 0.671 | 0.413 | 1.266 (0.720 – 2.227) |
| TT | 9 (9.3) | 5 (5.0) | 1.410 | 0.235 | 1.964 (0.634 – 6.084) |
| Allele frequency | |||||
| G | 132 (68.1) | 152 (75.24) | 1.410 | 0.235 | 0.509 (0.164–1.578) |
| T | 62 (32.0) | 50 (24.75) | 2.013 | 0.156 | 1.499 (0.856–2.625) |
| HWE (p) | 0.816 | 0.789 | |||
| Smal (rs2241766) | 97 (100.0) | 101 (100.0) | 1.126 | 0.569 | |
| TT | 60 (61.9) | 68 (67.3) | 0.648 | 0.421 | 0.787 (0.439–1.411) |
| TG | 36 (37.1) | 31 (30.7) | 0.911 | 0.340 | 1.333 (0.738–2.405) |
| GG | 1 (1.0) | 2 (2.0) | 0.299 | 0.585 | 0.516 (0.046–5.780) |
| Allele frequency | |||||
| T | 156 (80.4) | 167 (82.7) | 0.299 | 0.585 | 1.939 (0.173–21.741) |
| G | 38 (19.6) | 35 (17.3) | 0.648 | 0.421 | 1.271 (0.709–2.278) |
| HWE (p) | 0.110 | 0.730 | |||
HWE: Hardy-Weinberg Equation; OR: odds ratio; CI: confidence interval