Table 2. Summary ORs and 95% CI of microRNA-146a rs2910164 polymorphisms and CHD risk.

Locus	N*	Allele		Recessive		Dominant		Homozygote		Heterozygote
		OR (95%CI) P	I2(%)	OR (95%CI) P	I2(%)	OR (95%CI) P	I2(%)	OR (95%CI) P	I2(%)	OR (95%CI) P	I2(%)
Total	10	1.12 (1.06-1.18) <0.01	11.2	1.19 (1.09-1.30) <0.01	0	1.12 (1.03-1.23) 0.012	43.6	1.23 (1.10-1.38) <0.01	9.6	1.06 (0.97-1.17) 0.211	46.7
Ethnicity
Asian	8	1.10 (1.04-1.17) <0.01	0	1.18 (1.08-1.29) <0.01	0	1.09 (0.99-1.20) 0.083	22.6	1.20 (1.07-1.35) <0.01	0	1.03(0.93-1.14) 0.631	30.5
Caucasian	2	1.25 (0.88-1.77) 0.205	66.5	1.47 (0.92-2.35) 0.108	0	1.33 (0.80-2.21) 0.277	75.0	1.74 (1.07-2.84) 0.025	13.4	1.29 (0.79-2.11) 0.312	70.9
Source of controls
Population	2	1.08 (0.95-1.22) 0.247	0	1.17 (0.96-1.42) 0.130	0	1.04 (0.85-1.27) 0.733	0	1.15 (0.89-1.49) 0.281	0	0.98 (0.80-1.22) 0.883	0
Hospital	6	1.11 (1.04-1.19) <0.01	0	1.18 (1.07-1.31) <0.01	0	1.11 (0.99-1.24) 0.067	40.9	1.22 (1.07-1.39) <0.01	23.8	1.04 (0.93-1.17) 0.470	47.0
Method
Taqman	4	1.15 (1.03-1.29) 0.017	50.0	1.24 (1.10-1.41) <0.01	0	1.14 (0.90-1.43) 0.281	67.3	1.23 (1.05-1.44) 0.012	41.9	1.05 (0.82-1.36) 0.698	69.9
PCR-RFLP	4	1.07 (0.97-1.19) 0.177	0	1.10 (0.94-1.28) 0.227	0	1.09 (0.91-1.31) 0.347	45.0	1.16 (0.94-1.43) 0.165	22.9	1.05 (0.87-1.28) 0.598	44.2
Age and sex matched	6	1.11 (1.03-1.19) <0.01	35.3	1.21 (1.08-1.35) <0.01	0	1.08 (0.90-1.29) 0.420	52.7	1.18 (1.02-1.37) 0.024	25.0	1.00 (0.83-1.22) 0.981	54.1
Controls in HWE	9	1.13 (1.06-1.20) <0.01	17.0	1.21 (1.10-1.33) <0.01	0	1.13 (1.03-1.25) 0.012	49.4	1.25 (1.11-1.41) <0.01	15.7	1.07 (0.92-1.25) 0.396	52.5

^* Numbers of comparisons. PCR-RFLP: polymerase chain reaction-based restriction fragment length polymorphism. HWE: Hardy-Weinberg equilibrium.