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. 2016 Dec 20;8(4):5761–5773. doi: 10.18632/oncotarget.14050

Table 1. Examples of Gene Ontology terms related to cancer-associated processes that are associated with PPFP peaks.

Word or phrase Examples of GO terms associated with PPFP peaks q-value
Actin/microtubule GO:0030029 actin filament-based process 9.56E-06
GO:0030036 actin cytoskeleton organization 4.83E-05
GO:0008154 actin polymerization or depolymerization 0.0215
GO:0030048 actin filament-based movement 0.0380
GO:0032886 regulation of microtubule-based process 0.0081
GO:0070507 regulation of microtubule cytoskeleton organization 0.0082
GO:0031110 regulation of microtubule polymerization or depolymerization .00155
Adhesion/junction GO:0016337 cell-cell adhesion 0.0034
GO:0034330 cell junction organization 0.0010
GO:0034329 cell junction assembly 0.0115
GO:0007160 cell-matrix adhesion 0.0160
GO:0045216 cell-cell junction organization 0.0184
GO:0031589 cell-substrate adhesion 0.0241
Apoptotic/cell death GO:0008219 cell death 2.02E-11
GO:0006915 apoptotic process 5.47E-11
GO:0010941 regulation of cell death 3.00E-06
Cell cycle/proliferation GO:0007049 cell cycle 6.32E-06
GO:0042127 regulation of cell proliferation 2.02E-05
Development GO:0001701 in utero embryonic development 6.49E-05
GO:0060284 regulation of cell development 0.0004
GO:0001944 vasculature development 0.0070
Folding/ubiquitin GO:0006457 protein folding 0.0015
GO:0016567 protein ubiquitination 0.0017
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 0.0068
GO:0061077 chaperone-mediated protein folding 0.0125
Glutathione/oxidative stress/reactive oxygen species GO:0006749 glutathione metabolic process 0.0082
GO:0034614 cellular response to reactive oxygen species 0.0465
GO:0034599 cellular response to oxidative stress 0.0324
Glycolysis GO:0006096 glycolysis 0.0018
GTP/RAS GO:0007264 small GTPase mediated signal transduction 1.88E-07
GO:0006184 GTP catabolic process 1.30E-06
GO:0046039 GTP metabolic process 1.98E-06
GO:0043547 positive regulation of GTPase activity 0.0001
GO:0046578 regulation of Ras protein signal transduction 4.19E-05
GO:0032318 regulation of Ras GTPase activity 0.0017
Migration/motility/locomotion GO:0030334 regulation of cell migration 0.0017
GO:2000147 positive regulation of cell motility 0.0111
GO:0040017 positive regulation of locomotion 0.0351
Wnt GO:0016055 Wnt receptor signaling pathway 0.0037
GO:0030111 regulation of Wnt receptor signaling pathway 0.0467