Table 2. Meta analysis results.
| Outcome | Variables | Number of studies | Number of patients | HRFEM (95% CIFEM) | PFEM |
|---|---|---|---|---|---|
| OS | ALL | 10 | 3919 | 1.51 (1.31–1.72) | 0.48 |
| Detection method | |||||
| IHC | 6 | 879 | 1.60 (1.21–2.13) | 0.24 | |
| TMA | 4 | 3040 | 1.48 (1.27–1.72) | 0.68 | |
| Analysis method | |||||
| Univariable | 4 | 529 | 1.63 (1.14–2.31) | 0.57 | |
| Mutivariable | 6 | 3390 | 1.48 (1.28–1.71) | 0.28 | |
| Antibody-catalog | |||||
| Clone 160112 | 6 | 1574 | 1.57 (1.28–1.93) | 0.60 | |
| Others | 4 | 2345 | 1.45 (1.21–1.73) | 0.20 |
HR: hazard ratio; CI: confidence interval; IHC: immunohistochemistry; TMA: tissue microarray; OS: overall survival; FEM: fixed effect model.