Figure 2. Use of β-blockers is correlated with a reduction in the proliferation rate of Stage I breast cancers.

(A) Retrospective analysis of 404 breast cancer patients was performed to determine if use of β-blockers correlated with the tumor Ki-67 index. Box and whiskers plot illustrating the lack of correlation between β-blocker use and breast tumor proliferative rate as determined by the Ki-67 index. (B) Stage I breast cancer patients from the retrospective study were stratified based on no β-blocker use (control), or the use of non-selective or selective β-blockers. Shown is a box and whiskers plot illustrating the significant correlation between non-selective β-blockers and reduced Ki-67 proliferative index.