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. 2016 Dec 24;8(4):6540–6554. doi: 10.18632/oncotarget.14145

Table 2. Pharmacologic inhibition of MRP4 increases sensitivity to 6-MP.

Pharmacologic Treatment μM Fold Sensitizationa
MDA-MB-231
MK571 50 2.94 *
MDA-MB-436
MK571 25 1.47 *
Tyrphostin AG 1478 10 2.86 **
BT549
MK571 50 1.76 **
Tyrphostin AG 1478 10 4.83 **

aSensitization by MRP4 inhibitors relative to vehicle treatment

* p < 0.05, ** p < 0.01