Figure 2. Cordycepin induces apoptosis through down-regulation of c-FLIPL.

The indicated cell lines were disposed with 0, 50, 100 and 200 μM cordycepin for 12 h A. or treated with 100 μM cordycepin for the indicated time B., then the whole-cell protein lysates were harvested and prepared for western blot analysis. C. The viability of H157-FLIPL and H157-lacz cells were measured by SRB assay after exposed to the indicated concentrations of cordycepin for 24 h. D. H157-FLIPL and H157-lacz cells were treated with 0, 50, 100 μM condycepin for 12 h, then whole cell lysates were collected for western blot analysis. Data represented mean ± SEM for three independent experiments each. L.E.: long exposure; S.E.: short exposure. *p < 0.05, **p < 0.01, ***p < 0.001