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. 2016 Dec 27;8(4):6691–6699. doi: 10.18632/oncotarget.14262

Figure 6. The schematic model of cordycepin-triggered apoptosis and autophagy in human NSCLC cells.

Figure 6

Cordycepin treatment stimulates extrinsic apoptosis pathway by inhibiting the expression of c-FLIPL. Furthermore, cordycepin also triggered autophagy through suppression of mTOR signaling pathway. Cordycepin-induced autophagy promoted apoptosis through degrading c-FLIPL.