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. 2016 Dec 27;8(4):6730–6741. doi: 10.18632/oncotarget.14268

Figure 4. GSK461364-mediated PLK1 inhibition exerts antitumoral activity against human neuroblastoma xenografts in mice.

Figure 4

Kaplan-Meier analysis of GSK461364-treated and control mouse cohorts in animals injected with A. SK-N-AS or B. IMR-32 cells. Red lines indicate duration of treatment. C. Micrographs show immunostainings for Ki67 to identify proliferating cells and cleaved caspase 3 to identify apoptotic cells in addition to hematoxylin & eosin staining (HE) for SK-N-AS xenograft tumors 3 days after start of treatment.