Figure 1. AR-Q784* produces a C-terminal truncated form of AR protein.
A. Predicted protein structure of AR-FL, AR-V7, or AR-Q784*. B. Immunoblotting for AR (using antibody against N-terminal region) in COS-7 cells transfected with AR-FL, AR-V7, AR-Q784*, or empty vector. C. Immunoblotting for AR (N-terminal) in PC-3 cells transfected with AR-FL, empty vector, or AR-Q784*, and treated with vehicle or 10nM DHT (24h).