Table 3. Univariate and multivariate Cox regression analyses of overall survival in breast cancer patients.

Variables	Univariate analysis		Multivariate analysis
	HR(95%CI)	P value	HR(95%CI)	P value
Age(years), ≦50 versus >50	1.245(0.446-3.502)	0.671
Menopausal status, Premenopausal versus Postmenopausal	1.462(0.520-4.112)	0.472
Tumor size(cm), ≦2 versus >2	2.411(0.856-6.791)	0.096
Lymph node status, negative versus positive	3.671(1.196-11.262)	0.023	0.821(0.147-4.587)	0.822
Grade I-II versus III	1.973(0.674-5.770)	0.215
ER status, negative versus positive	0.247(0.075-0.814)	0.022	0.408(0.052-3.194)	0.393
RR status, negative versus positive	0.190(0.051-0.708)	0.013	0.206(0.024-1.738)	0.147
HER-2/neu status, negative versus positive	5.156(1.754-15.157)	0.003	1.665(0.427-6.941)	0.462
TNM stage, I-II versus III	2.996(1.697-5.290)	0.000	2.729(1.103-6.755)	0.030
HOTTIP expression, low versus high	11.294(2.435-52.397	0.002	7.121(1.176-43.109)	0.033