Figure 1. Differences in miRNA expression in the frozen tissues between cancer tissues with recurrence and those without recurrence using a heat map for the preliminary study.

A total of 15 species of miRNAs showed significantly higher expression in cancer tissue than in noncancerous tissues; in addition, miRNAs from cancer tissues with recurrence rather than from cancer tissues without recurrence were selected. miRNAs were let-7a, -7d, -7e, miR-18b, -23c, -26b, -128a, -146b, -148b, -151-5p, -181c, -221, -222, -361, and -500.