Table 2. Association of mucins and associated O-glycans expression with clinicopathological characteristics.
N | MUC1 | MUC4 | MUC17 | MUC2 | MUC5AC | CA19-9 | Tn/STn-MUC1 | ||
---|---|---|---|---|---|---|---|---|---|
Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | |||
Age | < 60 years | 47 | 0.77 ± 0.09 | 1.31 ± 0.11 | 0.5 ± 0.07 | 1.71 ± 0.11 | 0.88 ± 0.09 | 1.21 ± 0.15 | 1.34 ± 0.07 |
≥60 years | 50 | 0.72 ± 0.08 | 1.27 ± 0.11 | 0.64± 0.06 | 1.8 ± 0.1 | 0.68 ± 0.09 | 0.98 ± 0.14 | 1.2 ± 0.07 | |
p-value | 0.76 | 0.79 | 0.093 | 0.54 | 0.1 | 0.25 | 0.37 | ||
Gender | Female | 57 | 0.74 ± 0.07 | 1.29 ± 0.1 | 0.57 ± 0.06 | 1.7 ± 0.1 | 0.71 ± 0.08 | 1.12 ± 0.14 | 1.28 ± 0.06 |
Male | 40 | 0.75 ± 0.1 | 1.29 ± 0.12 | 0.58 ± 0.08 | 1.84 ± 0.12 | 0.87 ± 0.11 | 1.04 ± 0.15 | 1.25 ± 0.09 | |
p-value | 0.67 | 0.96 | 0.68 | 0.25 | 0.32 | 0.41 | 0.61 | ||
Ethnicity | Caucasian | 74 | 0.73 ± 0.06 | 1.31 ± 0.09 | 0.56 ± 0.05 | 1.73 ± 0.09 | 0.83 ± 0.08 | 1.18 ± 0.12 | 1.22 ± 0.06 |
Other | 13 | 0.87 ± 0.18 | 1.31 ± .21 | 0.48 ± 0.12 | 1.85 ± 0.17 | 0.4 ± 0.12 | 0.45 ± 0.21 | 1.45 ± 0.15 | |
p-value | 0.51 | 0.95 | 0.58 | 0.79 | 0.027 | 0.021 | 0.15 | ||
Polyp site | Cecum | 8 | 0.65 ± 0.1 | 1.03 ± .14 | 0.75 ± 0.1 | 1.6 ± 0.16 | 0.75 ± 0.15 | 1.19 ± 0.24 | 1.15 ± 0.1 |
Ascending | 22 | 0.73 ± 0.12 | 1.28 ± .22 | 0.56 ± 0.19 | 1.96 ± 0.12 | 0.93 ± 0.24 | 1.01 ± 0.28 | 1.28 ± 0.15 | |
Transverse | 13 | 0.5 ± 0.15 | 1.11 ± 0.27 | 0.55 ± 0.16 | 1.43 ± 0.32 | 0.54 ± 0.25 | 0.84 ± 0.36 | 1.05 ± 0.14 | |
Descending | 12 | 0.68 ± 0.17 | 1.73 ± 0.19 | 0.55 ± 0.1 | 1.57 ± 0.19 | 0.59 ± 0.09 | 0.95 ± 0.21 | 1.35 ± 0.13 | |
Sigmoid | 21 | 0.74 ± 0.12 | 1.42 ± 0.16 | 0.43 ± 0.09 | 1.98 ± 0.15 | 0.79 ± 0.11 | 1.17 ± 0.22 | 1.3 ± 0.11 | |
Rectum | 19 | 1.02 ± 0.15 | 0.93 ± 0.2 | 0.59 ± 0.11 | 1.88 ± 0.19 | 1.06 ± 0.24 | 1.03 ± 0.28 | 1.39 ± 0.13 | |
p-value | 0.16 | 0.037 | 0.33 | 0.33 | 0.47 | 0.93 | 0.42 | ||
FH of colon cancer | no | 74 | 0.77 ± 0.07 | 1.27 ± 0.09 | 0.56 ± 0.05 | 1.72 ± 0.09 | 0.77 ± 0.08 | 0.97 ± 0.11 | 1.28 ± 0.06 |
yes | 17 | 0.62 ± 0.09 | 1.38 ± 0.14 | 0.49 ± 0.1 | 1.92 ± 0.11 | 0.76 ± 0.18 | 1.44 ± 0.25 | 1.13 ± 0.1 | |
p-value | 0.58 | 0.66 | 0.64 | 0.65 | 0.9 | 0.064 | 0.15 | ||
Tobacco | no | 29 | 0.63 ± 0.09 | 1.02 ± 0.13 | 0.51 ± 0.07 | 1.65 ± 0.15 | 0.89 ± 0.14 | 1.1 ± 0.18 | 1.28 ± 0.1 |
yes | 63 | 0.79 ± 0.08 | 1.43 ± 0.1 | 0.56 ± 0.06 | 1.8 ± 0.09 | 0.7 ± 0.08 | 1.02 ± 0.13 | 1.24 ± 0.06 | |
p-value | 0.3 | 0.021 | 0.78 | 0.52 | 0.27 | 0.51 | 0.84 | ||
Polyp size | <0.05 cm3 | 66 | 0.7 ± 0.07 | 1.3 ± 0.09 | 0.53 ± 0.06 | 1.78 ± 0.08 | 0.72 ± 0.08 | 0.98 ± 0.12 | 1.25 ± 0.07 |
≥0.05 cm3 | 24 | 0.83 ± 0.14 | 1.31 ± 0.16 | 0.68 ± 0.09 | 1.75 ± 0.17 | 0.98 ± 0.13 | 1.29 ± 0.21 | 1.32 ± 0.08 | |
p-value | 0.51 | 0.9 | 0.11 | 0.84 | 0.087 | 0.17 | 0.27 | ||
Number of polyps | <2 | 21 | 0.58 ± 0.14 | 1.3 ± 0.17 | 0.62 ± 0.11 | 1.91 ± 0.12 | 0.97 ± 0.17 | 1.28 ± 0.22 | 1.33 ± 0.13 |
≥2 | 75 | 0.79 ± 0.06 | 1.29 ±0.09 | 0.57 ± 0.05 | 1.71 ± 0.09 | 0.72 ± 0.07 | 1.02 ± 0.12 | 1.25 ± 0.06 | |
p-value | 0.034 | 0.99 | 0.76 | 0.44 | 0.2 | 0.35 | 0.41 | ||
Prior or subsequent colonoscopies with polyps |
<2 | 45 | 0.7 ± 0.08 | 1.05 ± 0.13 | 0.6 ± 0.08 | 1.48 ± 0.11 | 0.71 ± 0.1 | 0.99 ± 0.15 | 1.19 ± 0.07 |
≥2 | 21 | 0.69 ± 0.11 | 1.25 ± 0.14 | 0.6 ± 0.1 | 1.91 ± 0.14 | 0.84 ± 0.15 | 0.95 ± 0.2 | 1.35 ± 0.11 | |
p-value | 0.94 | 0.31 | 0.78 | 0.024 | 0.48 | 0.83 | 0.25 |
FH, family history; SE, standard error