Skip to main content
. 2016 Sep 29;8(4):7025–7038. doi: 10.18632/oncotarget.12347

Table 3. Expression of mucins and associated O-glycans in different colorectal polyp subtypes and corresponding adjacent normal colon.

NC HP NC SSA/P NC TA
MUC1 Mean ± SE 0.25±0.07 e 0.76 ± 0.09 b 0.09±0.02 l 0.53 ± 0.09 c,h 0.28±0.05 i 1.02 ± 0.09 c,k
Median (Min, Max) 0.1(0,1.4) 0.6(0.1, 2.1) 0.05(0, 0.3) 0.4(0.05, 2.4) 0.2(0, 1) 1(0.1, 2.4)
MUC4 Mean ± SE 1.87±0.11 1.66 ± 0.12 k 1.63±0.15 l 1.05 ± 0.12 c,e 1.25±0.12 1.21 ± 0.12
Median (Min, Max) 2.1(0.2, 2.55) 1.8(0.3, 2.7) 1.8(0.1, 2.4) 1(0.05, 2.7) 1.2(0.05, 2.4) 1.3(0.1, 2.4)
MUC17 Mean ± SE 0.11±0.03 f 0.37 ± 0.05 c,l 0.06±0.02 l 0.85 ± 0.08 c,f,g 0.24±0.05 0.47 ± 0.07 j
Median (Min, Max) 0.05(0, 0.7) 0.2(0.05, 1.2) 0(0, 0.3) 1(0.05, 2.1) 0.1(0, 1.2) 0.4(0, 1.4)
MUC2 Mean ± SE 2.31±0.09 2.09 ± 0.09 h 2.26±0.09 k 1.92 ± 0.08 b,g 2.21±0.06 i 1.35 ± 0.14 c,e,j
Median (Min, Max) 2.4(1.2, 2.7) 2.4(0.75, 2.7) 2.4(0.9, 2.7) 1.8(1.2, 2.7) 2.4(1, 2.7) 1.3(0.1, 2.7)
MUC5AC Mean ± SE 0±0 f 0.65 ± 0.08 c,l,i 0±0 l 1.24 ± 0.09 c,f,i 0.03±0.02 i 0.3 ± 0.08 c,f,l
Median (Min, Max) 0(0, 0) 0.6(0.15, 2.1) 0(0, 0) 1.2(0.15, 2.4) 0(0, 0.6) 0.06(0, 2.1)
Tn/STn-MUC1 Mean ± SE 0.23±0.05 f 1.42 ± 0.07 c 0.17±0.05 l 1.39 ± 0.08 c 0.39±0.05 i 1.13 ± 0.1 c
Median (Min, Max) 0.1(0, 0.8) 1.4(0.6, 2.7) 0(0, 0.8) 1.4(0.3, 2.4) 0.3(0, 1.6) 1.2(0, 2.4)
CA19-9 Mean ± SE 0.1±0.05 f 1.53 ± 0.17 c,i 0.04±0.02 l 1.72 ± 0.13 c,i 0.02±0.01 i 0.1 ± 0.03 c,f,l
Median (Min, Max) 0(0, 1.2) 1.8(0, 2.7) 0(0, 0.4) 2.1(0, 2.7) 0(0, 0.3) 0(0, 0.6)

ap < 0.05 vs. adjacent normal; bp < 0.005 vs. adjacent normal; cp < 0.0005 vs. adjacent normal; dp < 0.05 vs. HP; ep < 0.005 vs. HP; fp < 0.0005 vs. HP; gp < 0.05 vs. TA; hp < 0.005 vs. TA; ip < 0.0005 vs. TA; jp < 0.05 vs. SSA/P; kp < 0.005 vs. SSA/P; lp < 0.0005 vs. SSA/P

NC, adjacent normal colon; HP, hyperplastic polyps; SSA/P, sessile serrated adenoma/polyps; TA, tubular adenoma; SE, standard error; Min, minimum; Max, maximum